The mission of the RANO-Meningioma Working Group is to develop and validate standardized response assessment criteria for meningiomas in clinical trials, and to discover novel methods for earlier detection of drug activity or tumor resistance. By fostering international collaboration among experts, we aim to enhance the accuracy and consistency of meningioma evaluations, thereby advancing therapeutic development and improving patient outcomes.
Huang RY, Bi WL, Weller M, et al. Proposed response assessment and endpoints for meningioma clinical trials: report from the Response Assessment in Neuro-Oncology Working Group. Neuro Oncol. 2019; 21(1):26-36.
Response assessment of meningioma: 1D, 2D, and volumetric criteria for treatment response and tumor progression. Huang RY, Unadkat P, Bi WL, George E, Preusser M, McCracken JD, Keen JR, Read WL, Olson JJ, Seystahl K, Le Rhun E, Roelcke U, Koeppen S, Furtner J, Weller M, Raizer JJ, Schiff D, Wen PY. Neuro Oncol. 2019 Feb 14;21(2):234-241.
Rogers L, Barani I, Chamberlain M, et al. Meningiomas: knowledge base, treatment outcomes, and uncertainties. A RANO review. J Neurosurg. 2015; 122(1):4-23.
Kaley T, Barani I, Chamberlain M, et al. Historical benchmarks for medical therapy trials in surgery- and radiation-refractory meningioma: a RANO review. Neuro Oncol. 2014; 16(6):829-840.

Associate Professor of Neurosurgery
Mass General Brigham
Brigham and Women's Hospital
Boston, MA, USA

Associate Professor of Radiology
Director, Neuroradiology Division
Mass General Brigham
Brigham and Women's Hospital
Boston, MA, USA
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